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  • 一抗-單抗MouseAnti-AFP(A2)antibody甲胎蛋白單克隆抗體(包被)
產(chǎn)品名稱:

一抗-單抗MouseAnti-AFP(A2)antibody甲胎蛋白單克隆抗體(包被)

產(chǎn)品品牌: SOLARBIO/索萊寶 價格:
廠商性質(zhì): 生產(chǎn)廠家 產(chǎn)品時間: 2024-07-09
一抗-單抗MouseAnti-AFP(A2)antibody甲胎蛋白單克隆抗體(包被)
貨號:bsm-1621M
規(guī)格:0.1ml/0.2ml
產(chǎn)品應用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)

產(chǎn)品概述

品牌SOLARBIO/索萊寶

一抗-單抗MouseAnti-AFP(A2)antibody甲胎蛋白單克隆抗體(包被)

產(chǎn)品編號bsm-1621M
英文名稱AFP(A2)
中文名稱甲胎蛋白單克隆抗體(包被)
別    名Alpha Fetoprotein; AFP; alpha 1 fetoprotein; alpha fetoglobulin; alpha Fetoprotein; Alpha fetoprotein precursor; FETA; HPAFP.
研究領(lǐng)域 
抗體來源Mouse
克隆類型Monoclonal
克 隆 號A2
交叉反應Human, 
產(chǎn)品應用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量65kDa
細胞定位分泌型蛋白 
性    狀Lyophilized or Liquid
濃    度1mg/1ml
免 疫 原Full length plasma AFP protein
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
生 產(chǎn) 商BIOSS
PubMedPubMed
產(chǎn)品介紹background:
Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries. 

Subunit:
Dimeric and trimeric forms have been found in addition to the monomeric form.

Subcellular Location:
Secreted.

Tissue Specificity:
Plasma. Synthesized by the fetal liver and yolk sac.

Similarity:
Belongs to the ALB/AFP/VDB family. 
Contains 3 albumin domains.

Gene ID:
174

Database links:

Entrez Gene: 174 Human

Omim: 104150 Human

SwissProt: P02771 Human

Unigene: 518808 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

AFP是由胚胎卵黃囊細胞,胚胎肝細胞和胎兒腸道細胞合成的一種糖蛋白。主要用于原發(fā)性或轉(zhuǎn)移性肝細胞癌、肝樣胃癌和性腺或性腺外某些生殖細胞腫瘤(如內(nèi)胚竇瘤)的診斷和鑒別診斷。
AFP敏感度較低,特異性強,大約60%左右的肝細胞肝癌陽性,在低分化腫瘤中常呈陽性表達。
該抗體與bsm-1622M(檢測)(Anti-Alpha Fetoprotein)配對使用;主要用于ELISA試劑盒,膠體金試劑條制備生產(chǎn)都很好。大量訂購可來電商議。
產(chǎn)品圖片

Protein: AFP lysate; 
Primary: mouse Anti-AFP(A4) (bsm-1622M) at 1:300; 
Secondary: HRP conjugated Goat-Anti-mouse IgG(bs-0296G-HRP) at 1: 5000; 
Predicted band size: 65 kD
Observed band size: 65 kD

Protein: CEA lysate; 
Primary: mouse Anti-AFP(A4) (bsm-1622M) at 1:300; 
Secondary: HRP conjugated Goat-Anti-mouse IgG(bs-0296G-HRP) at 1: 5000; 
Predicted band size: 65 kD
Observed band size: 65 kD

每一種抗體可以分別標記20種不同的標記物:

Alexa Fluor 350 APCCy7 HRP
Alexa Fluor 488Biotin FITC PE 
Alexa Fluor 555 Cy3 Gold RBITC
Alexa Fluor 647 Cy5.5  PE-Cy3PE-CY7
AP Cy5 PE-CY5PE-CY5.5 

 

一抗-單抗MouseAnti-AFP(A2)antibody甲胎蛋白單克隆抗體(包被) 訂購說明:

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一抗-單抗MouseAnti-AFP(A2)antibody甲胎蛋白單克隆抗體(包被) 運輸說明:

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